GHS guidance: Application of criteria in 3.8.1.1 and 3.8.1.6 for serious adverse health effects (acute toxicity)

Application of criteria in 3.8.1.1 and 3.8.1.6 showing that a substance should not be classified into the specific target organ toxicity (single exposure) hazard class when the target organ effect(s), following a single exposure, are serious adverse health effects (i.e. lethality) meeting the acute toxicity hazard classification criteria 

(Ref. Doc.: ST/SG/AC.10/C.4/2020/14, example 1)